This article demonstrates that restoring expression of the annexin A1 protein in prostate cancer cells induces programmed cell death (apoptosis). This is important since this suggest that annexin A1 may possible target for prostate cancer therapy.
This article demonstrates that annexin A2 protein expression is commonly loss in early stage prostate cancer, but that expression is paradoxically restored in high grade prostate cancer. This findings suggest that annexin A2 mya be a useful diagnostic and prognostic prostate cancer biomarker.
This manuscript demonstrates for the first time that prostate cancer cells stop producing the Annexin A1 protein.
This article demonstrates that annexin A1 expression is reduced in greater than 90% of early stage prostate cancers and pre-malignant lesions (HGPIN).
This article describes a novel three-dimensional cell culture model to study prostate cancer.